Chandra Shekar "Chandram" loves and marries Gowri. Soon, Chandram gets a job in an estate owned by Surendra Nath a decadent person who behaves like a gentleman and provides good hospitality. Later, once Gowri is alone, tries to molest her but Chandram arrives in time, and the quarrel ensues into the death of Surendra Nath. Chandram is sentenced to death but, on the way to prison, the police van meets with an accident and all occupants are dead.

The film begins on, two soulmates Seetapathi (Subbaraya Sarma) & Major Pratapa Rao (Abhishith Varma) fixing up their children, Sivudu (Rajendra Prasad) & Parvati's (Amurtha) alliance in their childhood. But unfortunately, the children grows up with rivalry, so, the elders separate them. After 10 years, they meet unknowingly and an incident makes Parvati misunderstand Sivudu as a thief. Eventually, the elders arrange their get-together, Here they truly fall in love when both the elders burst out and forcibly arrange the children's marriages with unknown people. At last, Sivudu brings out the truth and reunites the elders. Finally, the movie ends on a happy note with the marriage of Sivudu & Parvati.

It's about friendship between two friends and how their life changes when a new girl comes into their life and how their friendship will be impacted upon her arrival where a tiny misunderstanding leads to a war between two close friends.

Pilla Nuvvu Leni Jeevitham is the kind of film which borrows a little bit of everything from the magic recipe of a commercial entertainer, although it doesn't quite leave a mark of its own in the end.